Joined Mar 2015
2,804 Posts | 702+
Europe
How much comment is there about temper and politically important decisions of politically important persons afflicted by chronic pain due to various health conditions?
This:
pmc.ncbi.nlm.nih.gov
discusses the leg ulcers of Henry VIII.
A conclusion giving 2 other cases:
This:
500 years later: Henry VIII, leg ulcers and the course of history - PMC

A conclusion giving 2 other cases:
Any other notable cases?Persistent chronic leg ulcers have been shown to seriously adversely affect quality of life even in the age of modern medical treatment and analgesia.17 For Henry, racked with pain and repetitive infection, his ulcers regularly cauterized with red-hot irons, the situation must have been intolerable. The effect of chronic pain on the temperament is well recognized and the actions of many a historical figure have been linked to their personal physical misery. Judge Jeffries (1645–1689), widely known as the ‘Hanging Judge’ for his merciless punishment of King James II's enemies after the Monmouth Rebellion, was reputed to be in such a foul temper because of the bladder stones bouncing up and down on his trigone while travelling to the Bloody Assizes in a poorly-sprung carriage over potholed roads;18 and Napoleon Bonaparte's painful haemorrhoids left him sullen and quick to anger, unable to survey his troops by horseback at the Battle of Waterloo.19 Henry's vile temper was undoubtedly influenced by his clinical situation. Although he did not bear his suffering with fortitude, and his latter years were characterized by frequent tempestuous rages and cruelty, viciously turning on those that he had once patronised, he was courageous in his refusal to lie a-bed, allowing a fleeting glimpse of the valiant prince he used to be.