Compromise of 1850 with its Fugitive Slave Law
The Dred Scott Decision
The Tariff of 1857
The elections of 1852 and '56 were both won by Northerners who were friendly to the South. In fact almost every presidential election prior to 1860 was either won by a Southerner or a Northerner who was friendly to the South.
A lot of this was perception rather than reality, but perception trumps reality everytime. Real or not, my point was that the North was getting fed up with compromising with the South. Maybe I misspoke about compromise without compensation. It would be more accurate for me to say the North was just getting fed up with compromise.